Pharmacological effects pharmacodynamics product is a potent a2-adrenoceptor agonist, has obvious sedation, analgesia and muscle relaxation. Although the race many pharmacological effects similar to morphlne fluphenazine, but cats, horses and cattle do not cause central nervous system stimulation, but the cause sedation and central inhibition. Muscle relaxant effect on its inhibition in the central nerve impulse conduction level related to the intramuscular injection often induce vomiting cats, dogs also occasional vomiting.

Xylazine cardiovascular and respiratory effects of flux, the initial rise in blood pressure after administration most animals, but then reflected by reduced pressure, for a long time blood pressure, heart rate, bradycardia. In addition, the drug can reduce sympathetic activity, enhanced vagal activity, may be cited in ruminants | from excessive secretion of saliva. The role of breathing is breathing frequency drops. There are certain uterine smooth muscle stimulant, can increase uterine muscle tension cattle and intrauterine pressure, pregnancy livestock caution.

Pharmacokinetics This product can rapidly absorb intramuscular injection, but not completely absorbed irregular, different species and bioavailability of large individual differences between intramuscular injection bioavailability, Ma 40% to 48%, sheep of 17% to 73% dogs 52 to 90%. Intramuscular injection of 10 to 15 minutes function. Duration of effect depends on the dose, typically last 1.5 hours. Drugs are extensively metabolized in the body, rapid metabolism, elimination half-life of 23 minutes sheep, horses 50 minutes, 36 minutes cattle, dogs 30 minutes.

Drug interactions (1) drugs with chloral hydrate, sodium pentobarbltal or thiopental and other central nervous inhibition, can enhance the inhibitory effect.

(2) It can enhance the analgesic effect of ketamlne, muscle relaxation, which may antagonize central excitatory response.

(3) may be combined with epinephrine induced arrhythmias.

[Role and use of chemical Baoding medicine. Sedation, analgesia and muscle relaxation, mainly for chemical domestic and wild animals, Baoding and basic anesthetic effects.

[Dosage intramuscular injection: one volume, weight per 10kkg, cow horse 0.5 ~ lmla 0.05 ~ 0.15ml; Yang 0.05-0.1ml; dogs, cats 0.5-0.1ml; deer 0.05-0.15ml.

(1) dogs, cats medication often vomiting, muscle tremors, bradycardia, respiratory rate decrease etc. In addition, increased urination in cats.

(2) ruminants sensitive to the chemicals, after treatment showed increased salivation, ruminal atony, distention, reverse vomiting, diarrhea, bradycardia and movement disorders, late pregnancy, premature birth or miscarriage cows will appear.

Can occur after (3) equine medicine muscle tremors, bradycardia, respiratory rate decreased sweating, increased intracranial pressure and so on.

Adverse reactions (1) dogs, cats medication often vomiting, muscle tremors, bradycardia, respiratory rate decrease etc. In addition, increased urination in cats.

(2) ruminants sensitive to the chemicals, after treatment showed increased salivation, ruminal atony, distention, reverse vomiting, diarrhea, bradycardia and movement disorders, late pregnancy, premature birth or miscarriage cows will appear.

Can occur after (3) equine medicine muscle tremors, bradycardia, respiratory rate decreased sweating, increased intracranial pressure and so on.

(1) dairy animal disabled.

(2) Horse intravenous injection speed should be slow, administration may be prior to injection of small doses of atropine, in order to avoid the occurrence of cardiac conduction block.

Front (3) bovine FDA should fasting predetermined time, and atropine; surgery should adopt a prone orientation, and the lower head, to prevent foreign matter and pneumonia during cardiopulmonary compression rumen reduce flatulence. Cattle in late pregnancy should not be applied.

(4) dogs, cats medication can cause vomiting.

(5) there is respiratory depression, heart disease, kidney dysfunction and other symptoms of Huanchu caution.

(6) poisoning, available a2 blockers and atropine and other rescue.

Composition

Each ml contains

Xylazine ......................100mg

Indications:

Xylazine should be used in horses and Cervidae (Fallow Deer. Mule Deer, Sika Deer, White-Tailed Deer and Elk) when it is desirable to produco a state of sedation accompanied by a shorter period of analgesia.

Dosage and Adminstration:

Dosage intramuscular injection: one volume, weight per 10kkg, cow horse 0.5 ~ lmla 0.05 ~ 0.15ml; Yang 0.05-0.1ml; dogs, cats 0.5-0.1ml; deer 0.05-0.15ml.